Knees for You Guide to Knee ReplacementServing the Patient Community since 12/18/2006 Patricia Walter Owner/Webmaster |
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Interview with Philipp Lang - The ConforMIS Inc. founder and CEO
on custom-made implants, how the company was able to raise $50
million in a difficult investment climate and why ConforMIS is a lot
like Dell Computers. Updated 1/20/2010
READ FULL ARTICLE ...Lang told MassDevice about the genesis of ConforMIS, why its technology is a radical departure from standard orthopedic implant technology, how the company plans to expand the platform beyond knees to other large joints and how it managed to raise $50 million in a Series D round in the worst investment climate in recent memory... ...The key issue with today's standard devices is
that they come off the shelf, they come typically in six or seven
different sizes and they have to fit any patient, irrespective of
their body build — if they're tall or small, if they're large or
petite, when they're pre-manufactured you have to fit the patient to
the implant. Meaning you have to cut away a lot of tissue, primarily
bone, in order to fit the patient with the implant. ...In terms of large joints, knee is the biggest segment. I believe it's actually a little bigger than spine. Hip is the second-largest segment, so very attractive, and shoulder is a small segment today, but very high-growth. In fact, from a growth perspective, it's the highest growth of all. The short answer is these are all very significant markets and we have a significant opportunity because we're coming in with a technology that is so different. We've pretty much covered all the joints and the clinical applications. That's really the plan here, to build out this pipeline. It's truly platform technology and the plan is really to build this out. There's another benefit that we sort of learned later in the game. If you think for a moment about just-in-time manufacturing, in the 1980s PCs were generally sitting in a warehouse and you ordered one of those. Dell came up with this concept of "order your custom laptop or your custom PC and we'll ship it in three weeks." In a sense, we're doing exactly this kind of model in manufacturing orthopedics. We're doing it with the implants, but the other aspect here is that we have novel technology where we replace traditional instrumentation. Traditional orthopedic implants are implanted using 30 to 40 pieces of instrumentation. These metal instruments are very expensive - they cost between $20,000 and $30,0000. They're multi-use, but the manufacturers have to provide them, typically for free, to the hospitals. And the hospitals have to store them and autoclave them, so one set of instruments is with the patient in surgery and the other set is outside being cleaned after the last surgery. It's a huge inventory in the hospital. We have replaced this with highly accurate, highly reproducible disposable instruments that are also patient-specific. Everything is shipped literally in a FedEx box directly to the hospital. You place the box on the OR table, everything is sterile inside. The setup is much quicker than with traditional instrumentation and the hospitals don't have to manage the inventory anymore. They don't have to do the sterilization anymore. It's much easier to handle for the hospitals.
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