Knees for You Guide to Knee Replacement

Serving the Patient Community since 12/18/2006    Patricia Walter Owner/Webmaster

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Effect of Vitamin D for Symptomatic Osteoarthritis Study

January 9, 2013

Read Full Study Here

ABSTRACT

ImportanceKnee osteoarthritis (OA), a disorder of cartilage and periarticular bone, is a public health problem without effective medical treatments. Some studies have suggested that vitamin D may protect against structural progression.

Objective To determine whether vitamin D supplementation reduces symptom and structural progression of knee OA...

Results Eighty-five percent of the participants completed the study...

...Conclusion and Relevance Vitamin D supplementation for 2 years at a dose sufficient to elevate 25-hydroxyvitamin D plasma levels to higher than 36 ng/mL, when compared with placebo, did not reduce knee pain or cartilage volume loss in patients with symptomatic knee OA.

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